Janis Joplin leads Big Brother & The Holding Company in this quintessential song describing the rock "dance concert" scene in San Francisco. The "Two" in the song title refers to the Avalon and Fillmore, the leading psychedelic venues in San Francisco. The Monterey Pop Festival held June 16-18, 1967, put the growing psychedelic rock movement on the map and catapulted the careers of Jimi Hendrix (who set his guitar on fire), The Who, Janis Joplin, and Otis Redding. Big Brother's Combination of The Two wound up on the Cheap Thrills album which was the number 1 album for the year 1968. Note at the end of the video an open-mouthed Mama Cass from the Mamas and the Papas.